Question 1

How comprehensive is the drug list?

Accepted Answer

The tool covers several hundred of the most commonly prescribed drugs across major therapeutic categories. Rare or newly approved drugs may not be included — always check multiple sources for complex or unlisted drug combinations.

Question 2

Does the tool check for food and herbal interactions?

Accepted Answer

Yes — common food and supplement interactions are included: grapefruit juice (CYP3A4 inhibition affecting statins, calcium channel blockers, DOACs), St John's wort (potent CYP3A4 inducer), high-dose vitamin K (reversing warfarin), caffeine, and tyramine-rich foods with MAOIs.

Question 3

How should I use this in patients on ≥10 drugs?

Accepted Answer

For polypharmacy, consider deprescribing first: remove drugs without a current indication, duplicate therapy, or those with unfavourable risk-benefit. Then run the interaction checker on the remaining essential drugs. Be aware that the number of flagged interactions rises rapidly with the number of drugs screened; clinical filtration is needed.